If you make an early-bound call to a method M of an object of type T1 that was returned by AppDomain.CreateInstanceAndUnwrap(string, string), and that method makes an early-bound call to a method of an object of type T2 in an assembly C other than the current assembly or the assembly containing T1, assembly C is loaded into the current application domain. This loading occurs even if the early-bound call to T1.M() was made in the body of a System.Reflection.Emit.DynamicMethod, or in other dynamically generated code. If the current domain is the default domain, assembly C cannot be unloaded until the process ends. If the current domain later attempts to load assembly C, the load might fail.